Ex Vivo Assays
CIDP Preclinical laboratory has developed studies on ex vivo model from human skin explants. These explants are obtained from surgical waste after an abdominoplasty or mammoplasty reduction.
The Ex Vivo model:
- Is a viable full thickness skin (consisting of both the epidermis and dermis) that can be maintained in culture up to 10 days.
- Allows to work in conditions close to the in vivo model - Skin explants contain all cell types resident in the skin which are capable of exerting their physiological effects on the tissue and neighboring cells.
- Allows an adaptable application according to the product (active ingredients, finished products or formulated products) topically or directly in the culture medium.
Examples of studies that can be donne via the Ex Vivo model: