Dermocosmetics Clinical Research

CIDP Clinical Research comprises a team of investigators, pharmacists, clinical trial managers, medical writers, and data managers. The team works closely with more than 100 health professionals specialised in different therapeutic areas. The geographical locations of our 5 centres in Brazil, India, Mauritius, Romania, and Singapore enable access to a wide panel of multi-ethnic volunteers and the ability to conduct multi-centric studies.

DERMOCOSMETICS STUDIES

SAFETY STUDIES

  • Patch tests : Single, HRIPT, phototoxicity, photosensitisation
  • Non-comedogenic test
  • Stinger test
  • Eye instillation
  • Use tests

EFFICACY STUDIES

‚Äč

  • Anti-acne/Anti-sebum
  • Anti-ageing (Elasticity/Firmness/Lifting, Anti under-eye bags and anti-hollow cheeks, Cell renewal, Anti-wrinkles)
  • Anti pollution studies
  • Anti Dark Circle/Anti Dark Spots
  • Astringent effect
  • Complexion homogeneity and complexion radiance
  • Moisturising effect
  • Rosacea
  • Whitening/tanning effect
  • In-vitro assessment of skin lightening on artificial skin (BSP#50)
  • Shaving irritations
  • Skin roughness
  • Anti-dimples/anti-stretch marks
  • Anti-perspirant
  • Sniff test
  • Exfoliating effect
  • Hair removing efficacy
  • Determination of the wound healing effect of your product
  • Skin barrier protection/skin barrier recovery and wound healing

MAKE-UP STUDIES

  • Mascara
  • Skin foundation and powder
  • Lipstick
  • Make-up removal
  • Nail studies

CAPILLARY STUDIES

WELL-BEING

PHOTOBIOLOGY TESTING

In the field of photobiology, we offer a wide range of in vivo as well as in vitro tests that are performed in accordance with the latest guidelines by Cosmetics Europe (formerly COLIPA), International Standards (ISO guidelines) or FDA guidelines.

  • Very water resistance testing
  • Sun protection factor studies
  • UVA protection studies
  • Photosensitisation / Phototoxicity test
EQUIPMENT

Our centres are equipped with the latest technologies for the realisation of clinical trials:

  • Biometrology: corneometer, sebumeter, tewameter, pH meter, mexameter, moisturemeter, elastimeter, amongst others
  • Photobiology: solar simulators – Multiport, ORIEL and Narrow-Band UVB lamp
  • Imaging: VISIA systems, 3D optical imaging (PRIMOS), Lightcam, Visioscan, Dermascan
  • Colorimetry: spectrocolorimeter, chromameter

 

Our state-of-art facilities are temperature and humidity controlled which allow us to conduct studies as per the required environmental conditions.

INNOVATIVE PROTOCOL: ANTI-POLLUTION CLAIM

CIDP proposes novel standard methodologies - in vitro and in vivo tests - to substantiate the anti-pollution claim of cosmetics products.

 

In vitro anti-pollution test on Cell and Tisue (Explants and 3D Reconstructed Human Epidermis) models

In vitro protocols to evaluate the protective and repairing efficacy of a cosmetic product against the dtrimental impact of pollutants on the skin:

  • Standard protocol to determine the efficacy of cosmetic products against the oxidative stress triggered by pollutants
  • Standard protocol to determine the efficacy of cosmetic products against ageing effect of pollutants (monitoring the level of MMP-1)
  • Standard protocol to determine the efficacy of comestic products against the inflammatory effect of pollutants cytokines (IL-6, TNT-a, IL-1...) and mediators (nitric oxide) 

In vivo anti-pollution test:

CIDP has developped a pollution exposure system to allow in-vivo controlled exposure to pollutants (O3, Ambient particles...). This unique system allows online monitoring and control of the concentration and flux of different pollutants to which the skin is exposed to.

  • Clinical protocol to evaluate the protective and repairing efficacy of a cosmetic product against  the detrimental impact of pollutants on the skin:
    • Study under standard conditions (standard concentration and flux of different pollutants) with biomarker evaluation
    • Study under real polluted conditions with bimarker, biophysical and photographic evaluations
  • Clinical protocol to evaluate the barrier and cleansing efficacy of anti-pollution
    • Study under standard conditions or under real polluted conditions
    • Efficacy of product determined by quantification of pollutants on the skin
INNOVATIVE PROTOCOL: BLUE LIGHT PROTECTION CLAIM

CIDP has set up a calibrated source of Blue Light to investigate the effect of Blue Light on the skin and substantiate anti-pigmenting and anti-ageing Blue Light claims for cosmetic products

In vitro protocols on Cell and Tissue (Explants and 3D reconstructed Human Epidermis) 

  • Standard protocol to determine the efficacy of cosmetic products against the oxidative stress triggered by Blue Light 
  • Standard protocol using melanocytes to determine the efficacy of cosmetic products against the pigmenting effect of Blue Light
  • Standard protocol to determine the efficacy of cosmetic products against ageing effect of Blue Light (monitoring the level of MMP-1)
  • Standard protocol to determine the efficacy of cosmetic products against the inflammatory effect of Blue Light (monitoring the level of proinflammatory cytokines (IL-6, TNF-a, IL-1…) and mediators (nitric oxide)

 

In vivo protocols

  • Standard protocol to determine the antipigmenting efficacy of cosmetic products against Blue Light by colorimetric measurements
  • Standard protocol to determine the anti-ageing efficacy of cosmetic products